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RESEARCH & PUBLICATIONS
DMPK research anchored in African biology.
Active projects across pharmacogenomics, drug discovery and infectious disease — published in peer-reviewed venues by network members.
ONGOING RESEARCH PROJECTS
Live programmes.
Active
Africa-specific CYP enzyme polymorphisms.
Characterising genetic variants in key metabolising enzymes across African populations to improve drug dosing guidelines.
Active
Characterisation of PZQ metabolism.
Characterising the metabolism of the anti-schistosomicide drug, praziquantel.
Ongoing
Malaria drug-candidate PK optimisation.
Pharmacokinetic studies supporting lead optimisation for a novel antimalarial chemical series.
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