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SERVICE & ASSAYS
Structured ADME assays for live drug-discovery programmes.
We characterise the metabolic and physical properties of new chemical entities with rapid turnaround and rigorous QA.
OUR ASSAY MENU
Tier 1 essentials. Tier 2 advanced characterisation.
Send a brief →
Tier 1
Essential screening
Core ADME data for early discovery.
Physicochemical
01
·
Solubility
·
Lipophilicity (LogD)
·
Membrane permeability (PAMPA)
Metabolic stability
02
·
Plasma protein binding
·
Metabolic stability (Human)
·
Metabolic stability (Rat / Mouse)
CYP enzyme inhibition
03
·
Reversible inhibition (ICâ‚…â‚€)
·
Time-dependent inhibition
·
Major isoform panel
Tier 2
Advanced lead characterisation
Deeper safety and distribution insight.
Permeability — MDCK
01
·
Madin-Darby Canine Kidney cell assay
·
Oral absorption prediction
Safety — hERG screen
02
·
Cardiac potassium channel inhibition
·
Critical pre-clinical safety filter
Distribution — Tissue binding
03
·
Brain, liver, lung binding
·
Inputs for accurate PK modelling
HOW WE WORK
Our process.
Confidential intake to audit-ready report — five steps, fully tracked in CDD Vault.
Submit sample & brief
Confidential intake with assay scoping.
Compound registration
Tracking via CDD Vault.
Assay execution
QA-controlled bioanalytical workflow.
Data analysis & QA
Validated against reference standards.
Report delivery
Audit-ready documentation.
“
The DMPK Africa network gives us a single front door to assay capacity across the continent — anchored in African biology, with the QA we need for sponsor submissions.
— Network sponsor, drug-discovery programme
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